Studies have suggested that, the total glutathione concentration found in the bodies of patients with Cardiovascular Disease, are lower than the glutathione concentration present in the bodies of healthy persons.
During the studies, subgroups of patients with different types of cardiovascular disease, both the cerebral infarction and cerebral hemorrhage, were found to have significantly lower levels of glutathione compared to the control groups.
After making adjustments for certain other puzzling factors, it was found that, the subjects with higher glutathione levels were at lower level of risk of cardiovascular disease than those with lower glutathione levels. This connection was most prominently found in the patients with lacunar infarction or cerebral hemorrhage.
These studies also suggest that reduced plasma total glutathione levels is a risk factor for developing Cardiovascular Disease, especially in cases of cerebral small vessel disease.
Some Australian researchers also established a similar link between glutathione and cardiovascular diseases. The cells were found to become more prone to damage by nitric oxide or peroxynitrite when the glutathione levels in the mitochondria of cultured brain cells were dropped.
Through the studies it was determined that a partial loss of glutathione occurred during cerebral stroke which further continues during the reintroduction of blood into the blocked area. Furthermore, infusion of glutathione monoethylester, a compound that can increase mitochondrial glutathione, decreased the volume of the area rundown of blood. The researchers concluded stating that these recent findings show that alterations in mitochondrial glutathione were likely to contribute to the severity of tissue damage in stroke and also other neurological disorders.
MaxGXL has been proven to raise glutathione levels by approximately 250-400% in humans as proven by tests in lymphocytes.
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